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Certificate of Analysis · MOTS-c · Certificate reference 050550

COA # COA-2026-955272 · certificate reference 050550 (printed on the certificate as Lot Number).

Independent third-party testing by ILS Laboratories, San Diego, CA, on one certificate covering purity, identity, endotoxin and sterility. The certificate links to the laboratory's verification portal.

Product: MOTS-c · 20 mg

Laboratory: ILS Laboratories, 8222 Vickers St Suite 106, San Diego CA 92111

Laboratory accreditation: ISO/IEC 17025 (as stated on the certificate)

The laboratory's portal shows this certificate at its verify link; the access code is printed on the certificate.

Certificate of analysis — full panel (RP-HPLC at 214 nm; identity by HPLC retention time vs. reference standard)

Report COA-2026-955272Tested 8/7/2026

Result
Purity · RP-HPLC at 214 nm
99.83% (laboratory specification ≥95.0%)
Identity · HPLC retention time vs. reference standard
MOTS-c, Confirmed
Labelled content
20 mg (20 mg unit tested)
Assayed content
20.84 mg (laboratory specification Report Only) (20 mg unit tested)
On the assayed figure
Reported as Net Peptide Content against a Report Only specification; the certificate sets no acceptance range.
Net peptide content
20.84 mg in the 20 mg unit tested
Fill volume
3 mL (20 mg unit tested)
Appearance
Good
Sample matrix
Lyophilized
Date received
07/16/2026
Heavy metals — Arsenic (As) · ICP-MS
0.088 (laboratory specification NMT 1.5 ppm) (PASS)
Heavy metals — Cadmium (Cd) · ICP-MS
0.027 (laboratory specification NMT 0.5 ppm) (PASS)
Heavy metals — Lead (Pb) · ICP-MS
0.047 (laboratory specification NMT 1.0 ppm) (PASS)
Heavy metals — Mercury (Hg) · ICP-MS
0.0928 (laboratory specification NMT 1.5 ppm) (PASS)
Heavy metals — Chromium (Cr) · ICP-MS
0.0289 (laboratory specification NMT 10.0 ppm) (PASS)
On the heavy-metals figures
Elemental impurities analyzed by ICP-MS per USP <233> methodology. Acceptance criteria are internal laboratory quality screening limits for research-use materials and do not represent evaluation against any specific pharmacopeial monograph or product specification.
Verify on ILS Laboratories

Verify this certificate with the laboratory at portal.ils-lab.com using access code FDJV7YCA. That confirms the document is genuine and was issued by them. It confirms the certificate, not your individual vial.

The laboratory’s PDF of report COA-2026-955272
ILS Laboratories certificate of analysis COA-2026-955272, page 1 of 2, for MOTS-c, certificate reference 050550: purity 99.83% against the laboratory's ≥95.0% specification, the identity result, net peptide content 20.84 mg, and the chromatogram.ILS Laboratories certificate of analysis COA-2026-955272, page 2 of 2, for MOTS-c, certificate reference 050550: the sterility and endotoxin entries, the laboratory's notes on method, and its verification details.

Endotoxin and sterility, on the same certificate

Endotoxin (USP <85>): 0.101 EU/mL (Reported)Sterility (PCR): No Growth (PASS)

About the laboratories: who tests our lots, the methods each uses and how to verify a certificate.

For Research Use Only. Not for human consumption.